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Young Angus "Mac" MacGyver creates a clandestine organization within the U.S. government, relying on his unconventional problem-solving skills to save lives.

Season 1, Episode 1: The Rising 

Angus "Mac" MacGyver and Jack Dalton, special agents for the Department of External Services (DXS), join forces to recover a missing bioweapon that has the ability to destroy hundreds of thousands of people with one single drop.