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Medium gaat over het leven van helderziende Alison Dubois. Alison is een jonge moeder die een balans probeert te vinden tussen het leven met haar gezin en het oplossen van misdaden met haar gaven om met de doden te communiceren. 

From Emmy Award-winning executive producer, creator and director Glenn Gordon Caron (Moonlighting) comes Medium, a chilling drama series inspired by the real-life story of research medium Allison Dubois. Patricia Arquette (Stigmata, Flirting with Disaster) stars as a young wife and mother who, since childhood, has been struggling to make sense of her dreams and visions of dead people. Allison DuBois (Arquette) is a strong-willed young mother of three, a devoted wife and law student who begins to suspect that she can talk to dead people, see the future in her dreams and read people''s thoughts. Fearing for her mental health, she turns for support to her husband Joe (Jake Weber, "U-571"), an aerospace engineer, who slowly comes to believe that what his wife is telling him just might be true. The real challenge is convincing her boss, D.A. Devalos (Miguel Sandoval) --